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Calcipotriol

Dermatologic Agents
CATEGORIES

Dermatologic Agents, Antipsoriatic Agents


ALIASES

Calcipotriol/Betamethasone Sandoz, Daivobet, Daivobet®, Daivonex, Daivonex®, Daivonex® Combipack, Dovobet, Dovobet®, Enstilar, Enstilar®, Kalcipotriol/Betametason Ebb, Xamiol, Xamiol®, Zoriaxiol


SUBSTANCES

calcipotriol, calcipotriol hydrate


ENVIRONMENTAL CONCERN: MODERATE
Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.

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MODERATE
Underlying data for P, B, T and risk are from Fass.

Below is Hazard and Risk for calcipotriol from Fass environmental information for Daivobet (betamethasone, calcipotriol) (downloaded 2018-11-07)


Hazard
Persistence: "Calcipotriol is not readily biodegradable. It has been tested according to the test guideline OECD 301F and a biodegradation of -2 ± 2% was found after 28 days."

Bioaccumulation: Log Pow, calcipotriol = 4.9.

Toxicity: No data.

Risk
"Because of the lack of data it is not possible to calculate a valid PNEC and a risk of environmental impact cannot be excluded."

REFERENCES

  1. Fass.se för vårdpersonal