pCure Labs
LABS

Search substance info

Dimenhydrinate

Histamine H1 Antagonists
CATEGORIES

Histamine H1 Antagonists, Antiemetics


ALIASES

Amosyt®, Arlevert, Calma, VALONTAN, Dramamine For Kids, Dramamine Orange, Dramamine Original Formula, Driminate, Gravol, Motion Sickness, Motion Sickness Original Formula, Motion Sickness Original formula, Motion Sickness Relief, Motion Sickness Relief Original Formula, Novamine, Original Formula Motion Sickness Relief, Pac-kit Motion Sickness, Physicianscare Dimenhydrinate Motion Sickness Relief, Soflax, Travel Ease, Travel Sickness, Vertirosan, Vomex A, Wal-dram, Xamamina


SUBSTANCES

dimenhydrinate


ENVIRONMENTAL CONCERN: MODERATE
Dimenhydrinate (Dramamine, Gravol and Vertirosan) is an over-the-counter drug used to prevent motion sickness. It is closely related to diphenhydramine HCl, or Benadryl. It is primarily a H1-antagonist, but also possesses an antimuscarinic effect.

Read More

MODERATE
Underlying data for P, B, T and risk are from Fass.se.

Dimenhydrinate is a 1:1 salt of diphenhydramine and 8-chlorotheophylline. See also diphenhydramine.

Below is Hazard and Risk from Fass environmental information for Calma (dimenhydrinate ) (downloaded 2018-10-25)


Hazard
Persistence: No data.

Bioaccumulation: Log Kow = -0.39.

Toxicity: No data.

Risk
Risk of environmental impact of dimenhydrinate can not be excluded as ecotoxicological data are missing.

"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of dimenhydrinate is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit 0,01 μg/L."

REFERENCES

  1. Fass.se för vårdpersonal