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Antihypertensive Agents

Antihypertensive Agents, Anti-Arrhythmia Agents, Vasodilator Agents, Calcium Channel Blockers, Dihydropyridines


Cardioplen, Delmuno, Feldíl, Felocor, Felodin, Felodipine 1A Pharma, Felodipine AL, Felodipine AbZ, Felodipine Actavis, Felodipine AstraZeneca, Felodipine Aurobindo, Felodipine CF, Felodipine Dura, Felodipine EuroGenerics, Felodipine Heumann, Felodipine Hexal, Felodipine Mylan, Felodipine Orifarm, Felodipine Ratiopharm, Felodipine STADA, Felodipine Sandoz, Felodipine Teva, Felodipine Zentiva, Felodipine-CT, Felodistad, Felogamma, Felogen, Felotens, Flodil, Folpik, Logimat, Logimax, Mobloc, Modip, Neofel, Parmid, Plendil, Presid, Preslow, Tazko, Triacor, Triapin, Triasyn, Unimax, Vachalpha



Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and blocks calcium influx through voltage-gated T-type calcium channels. Felodipine is used to treat mild to moderate essential hypertension.

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  11. European Medical Agency - National registers of authorised medicines
  12. pCure Product Definition
  13. pCure Standard Dissolving Test


  1. Drugbank, The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
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