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Ketotifen

Anti-Allergic Agents
CATEGORIES

Anti-Allergic Agents, Antipruritics, Histamine H1 Antagonists


ALIASES

Antihistamine Eye, Care One Allergy Eye, Care One Eye Itch Relief, Equaline Eye Itch Relief, Equate Eye Itch Relief, Equate Itchy Eye, Eye Itch, Eye Itch Relief, Good Neighbor Pharmacy Eye Itch Relief, Good Neighbor Pharmacy Itchy Eye, Good Sense Allergy Eye, Good Sense Eye Itch Relief, Good Sense Itchy Eye original prescription strength, Health Mart Eye Itch Relief, Itchy Eye, Itchy Eye Drops, Itchy Eye Relief, Itchy Eye original prescription strength, Ketotifen, Ketotifen Fumarate, Ketotifen STADA, Leader Allergy Eye, Leader Eye Itch Relief Drops, Smart Sense Allergy, Sunmark Eye Itch Relief, Topcare Eye Itch Relief, Totifen, Wal Zyr, Zaditen, Zaditen Defiante, Zaditen Novartis, Zaditen®, Zaditor, Zaditor Antihistamine Eye Drops, Zasten


SUBSTANCES

ketotifen, ketotifen fumarate


ENVIRONMENTAL CONCERN: MODERATE
A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis. [PubChem]

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IN SCOPE
MODERATE

REFERENCES

  1. Stockholms läns landsting. Miljöklassificerade läkemedel 2014–2015. Stockholm; 2014.
  2. Fick J, Lindberg RH, Tysklind M, Larsson DG. Predicted critical environmental concentrations for 500 pharmaceuticals. Regul Toxicol Pharmacol. 2010;58:516-23.

SOURCES

  1. Drugbank, The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
  2. PubChem, PubChem is the world's largest collection of freely accessible chemical information. Search chemicals by name, molecular formula, structure, and other identifiers
  3. ECHA, The European Chemicals Agency (ECHA) is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.
  4. EMA, The mission of the European Medicines Agency (EMA) is to foster scientific excellence in the evaluation and supervision of medicines, for the benefit of public and animal health in the European Union (EU).
  5. EU watch-list, Commission Implementing Decision (EU) 2018/840 of 5 June 2018 establishing a watch list of substances for Union-wide monitoring in the field of water policy pursuant to Directive 2008/105/EC of the European Parliament.
  6. Umweltbundesamt, Since its founding in 1974, the German Environment Agency (Umweltbundesamt – UBA) has been Germany’s main environmental protection agency.
  7. Naturvårdsverket, A public agency in Sweden that is responsible for environmental issues. The Agency carries out assignments on behalf of the Swedish Government relating to the environment in Sweden, the EU and internationally
  8. Läkemedelsverket, The Swedish Medical Products Agency (MPA) is the Swedish national authority responsible for regulation and surveillance of the development, manufacturing and marketing of drugs and other medicinal products.
  9. FASS, The Swedish environmental classification of pharmaceuticals at www.fass.se has now been running since October 2005. Since then a large amount of environmental information of pharmaceuticals has been published.
  10. Janusinfo, Janusinfo is providing drug information to support healthcare professionals in their everyday work. The website is the electronic means of communication of the Drug Therapeutic Committee and the Health and Medical Care Administration of the Stockholm County Council, Sweden.