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Ketotifen

Anti-Allergic Agents
CATEGORIES

Anti-Allergic Agents, Antipruritics, Histamine H1 Antagonists


ALIASES

Ketotifen STADA, Zaditen, Zaditen Defiante, Zaditen Novartis, Zaditen®, Zasten, Antihistamine Eye, Care One Allergy Eye, Care One Eye Itch Relief, Equaline Eye Itch Relief, Equate Eye Itch Relief, Equate Itchy Eye, Eye Itch, Eye Itch Relief, Good Neighbor Pharmacy Eye Itch Relief, Good Neighbor Pharmacy Itchy Eye, Good Sense Allergy Eye, Good Sense Eye Itch Relief, Good Sense Itchy Eye original prescription strength, Health Mart Eye Itch Relief, Itchy Eye, Itchy Eye Drops, Itchy Eye Relief, Itchy Eye original prescription strength, Ketotifen, Ketotifen Fumarate, Leader Allergy Eye, Leader Eye Itch Relief Drops, Smart Sense Allergy, Sunmark Eye Itch Relief, Topcare Eye Itch Relief, Totifen, Wal Zyr, Zaditen, Zaditor, Zaditor Antihistamine Eye Drops, Zasten


SUBSTANCES

ketotifen, ketotifen fumarate


ENVIRONMENTAL CONCERN: MODERATE
A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis. [PubChem]

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MODERATE
With the exception of B, he data on hazard and risk are based on previous environmental information on Fass.se. Environmental information is missing on fass.se ( 2018-11-01). It is voluntary for manufacturers to provide information about environmental impact on fass.se. Underlying data for B comes from the article Fick J et al. 2010.

Article Predicted critical environmental concentrations for 500 pharmaceuticals
Critical effect concentration (CEC) for ketotifen is 12 ng/L. Log P is set to 3.9.

REFERENCES

  1. Stockholms läns landsting. Miljöklassificerade läkemedel 2014–2015. Stockholm; 2014.
  2. Fick J, Lindberg RH, Tysklind M, Larsson DG. Predicted critical environmental concentrations for 500 pharmaceuticals. Regul Toxicol Pharmacol. 2010;58:516-23.