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Maprotiline

Antidepressive Agents, Second-Generation
CATEGORIES

Antidepressive Agents, Second-Generation, Adrenergic Uptake Inhibitors, Antidepressive Agents


ALIASES

Ludiomil®, Maprotilin Mylan, Maprotiline, Maprotiline Hydrochloride, Psymion


SUBSTANCES

maprotiline, maprotiline hydrochloride, maprotiline mesylate


ENVIRONMENTAL CONCERN: MODERATE
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder. Maprotiline is effective at reducing symptoms of anxiety associated with depression.

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MODERATE
Detailed information about this substance is missing and will added when a credible source of information has been identified.