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Oxaliplatin

Antineoplastic Agents
CATEGORIES

Antineoplastic Agents


ALIASES

Eloxatin, Oxaliplatin Accord, Oxaliplatin Actavis, Oxaliplatin Ebewe, Oxaliplatin Fresenius Kabi, Oxaliplatin Hospira, Oxaliplatin Pfizer, Oxaliplatin SUN, Oxaliplatin Teva, Oxaliplatin Vianex, Oxaliplatin Winthrop, Oxaliplatin medac


SUBSTANCES

oxaliplatin


ENVIRONMENTAL CONCERN: MODERATE
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as Folfox for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility. Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin®.

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MODERATE
Detailed information about this substance is missing and will added when a credible source of information has been identified.