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Oxytetracycline

Tetracyclines
CATEGORIES

Tetracyclines


ALIASES

Airikularum, Atecortin, Engemycin, Geokorton, Geonistin, Oxycort, Oxymycin, Oxytetracycline Augensalbe Jenapharm, Oxytetracycline Beral, Oxytetracycline Chevita, Oxytetral, Oxytetra-Mix, Posicycline, Sterdex, Terracort, Terracortril, Terracortril + Polymyxine B, Terramicina, Terramycin + Polymyxine B, Terricil, Tetran, Tetrasona, Trimovate, Vanacyclin


SUBSTANCES

oxytetracycline, oxytetracycline calcium, oxytetracycline dihydrate, oxytetracycline hydrochloride


ENVIRONMENTAL CONCERN: HIGH
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions. [PubChem]

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HIGH

This substance is an antibiotic (also called, anti-bacterial agent). All antibiotics are suspected to cause antibiotic resistance and we should therefore try to limit releasing it to Nature via our wastewater streams.

Some key facts from WHO

  • Antibiotic resistance is one of the biggest threats to global health. food security, and development today
  • Antibiotic resistance can affect anyone, of any age, in any country.
  • Antibiotic resistance occurs naturally, but misuse of antibiotics in humans and animals is accelerating the process.
  • A growing number of infections – such as pneumonia, tuberculosis, gonorrhoea, and salmonellosis – are becoming harder to treat as the antibiotics used to treat them become less effective.
  • Antibiotic resistance leads to longer hospital stays, higher medical costs and increased mortality.
Detailed information about this substance is missing and will added when a credible source of information has been identified.

REFERENCES

  1. Gao, P., Y. Ding, H. Li and I. Xagoraraki (2012). Occurrence of pharmaceuticals in a municipal wastewater treatment plant: Mass balance and removal processes. Chemosphere 88, 17-24.
  2. Chang, X. S., M. T. Meyer, X. Y. Liu, Q. Zhao, H. Chen, J. A. Chen, Z. Q. Qiu, L. Yang, J. Cao and W. Q. Shu (2010), Determination of antibiotics in sewage from hospitals, nursery and slaughter house, wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China. Environ Pollut. 158, 1444-1450.
  3. Li, B. and T. Zhang (2011). Mass flows and removal of antibiotics in two municipal wastewater treatment plants, Chemosphere 83, 1284-1289
  4. Yang, L. , Ying, G. , Su, H. , Stauber, J. L., Adams, M. S. and Binet, M. T. (2008), Growth‐inhibiting effects of 12 antibacterial agents and their mixtures on the freshwater microalga Pseudokirchneriella subcapitata. Environ Toxicol Chem, 27, 1201-1208
  5. Oliveira, R., McDonough, S., Ladewig, J., Soares, A., Nogueira, A., Domingues, I. (2013), Effects of oxytetracycline and amoxicillin on development and biomarkers activities of zebrafish (Danio rerio), Environ Toxicol Pharmacol, 36, 903-912,
  6. Ferreira, C., Nunes, B., de Melo Henriques-Almeida, J., Guilhermino, L., (2007), Acute toxicity of oxytetracycline and florfenicol to the microalgae Tetraselmis chuii and to the crustacean Artemia parthenogenetica, Ecotox Environ Safe,67, 452-458,