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Propiomazine

Hypnotics and Sedatives
CATEGORIES

Hypnotics and Sedatives, Histamine Antagonists, Antiemetics


ALIASES

Propavan, Dorevane, Indorm, Largon, Propavan, Propiomazine, Serentin


SUBSTANCES

propiomazine, propiomazine maleate


ENVIRONMENTAL CONCERN: MODERATE
Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors.

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MODERATE
There is no data for the T-value. The environmental information comes from Fass.se.

Below is Hazard and Risk from Fass environmental information for Propavan (propiomazine) (downloaded 2018-07-03)


Hazard
Persistence: "No degradation data are available."

Bioaccumulation: Log Pow = 4.79.

Chronic toxicity: No data available.

Risk
"The PEC/PNEC ratio could not be determined since no ecotoxicological test results are available."

REFERENCES

  1. Fass.se för vårdpersonal